Wide Dissemination of GES-Type Carbapenemases in Acinetobacter baumannii Isolates in Kuwait

Detection of Carbapenemases Emerging in Acinetobacter baumannii Clinical Isolates by Modified Hodge Test

Introduction: Acinetobacter baumannii, a known causative agent of nosocomial infections, is one of the highly antibiotic-resistant gram-negative bacilli. Carbapenem-resistant Acinetobacter isolates are increasingly reported worldwide. Carbapenems such as imipenem and meropenem are efficient antimicrobial agents commonly used for the treatment of infections caused by multi- resistant A. baumanni...

OXA-type carbapenemases in Acinetobacter baumannii in South America.

Acinetobacter baumannii is an opportunistic pathogen that is frequently involved in outbreaks of infection, occurring mostly in intensive care units. The increasing incidence of carbapenem resistance in A. baumannii worldwide is a concern since it limits drastically the range of therapeutic alternatives. The most important mechanism of carbapenem resistance is the enzymatic hydrolysis mediated ...

Prevalence of Carbapenemases in Acinetobacter baumannii

Association of doripenem resistance with OXA-type carbapenemases in Acinetobacter baumannii isolates

OBJECTIVES To evaluate the in vitro activity of doripenem in Acinetobacter baumannii (A. baumannii) clinical isolates that possess different OXA-type carbapenemases, and to evaluate the roles of these enzymes in the development of carbapenem resistance. METHODS This retrospective study was conducted with 25 A. baumannii isolates at Sakarya University Training and Research Hospital, Sakarya, T...

Detection of kpc-type Carbapenemases in Clinical Isolates of Acinetobacter baumannii

Background: Multidrug-resistant Acinetobacter baumannii is associated with life threatening nosocomial infections and hospital outbreaks. The organism is resistant to most commonly used antibiotics including carbapenems. Aim and Objectives: To study carbapenemase production among multidrug-resistant clinical isolates of A. baumannii. Material and Methods: Fifty multidrug-resistant A. baumannii ...